Human intestinal bacteria as reservoirs for antibiotic resistance genes.
نویسندگان
چکیده
Human intestinal bacteria have many roles in human health, most of which are beneficial or neutral for the host. In this review, we explore a more sinister side of intestinal bacteria; their role as traffickers in antibiotic resistance genes. Evidence is accumulating to support the hypothesis that intestinal bacteria not only exchange resistance genes among themselves but might also interact with bacteria that are passing through the colon, causing these bacteria to acquire and transmit antibiotic resistance genes.
منابع مشابه
The human microbiome harbors a diverse reservoir of antibiotic resistance genes.
The increasing levels of multi-drug resistance in human pathogenic bacteria are compromising our ability to treat infectious disease. Since antibiotic resistance determinants are readily exchanged between bacteria through lateral gene transfer, there is an increasing interest in investigating reservoirs of antibiotic resistance accessible to pathogens. Due to the high likelihood of contact and ...
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ورودعنوان ژورنال:
- Trends in microbiology
دوره 12 9 شماره
صفحات -
تاریخ انتشار 2004